男友太凶猛1v1高h,大地资源在线资源免费观看 ,人妻少妇精品视频二区,极度sm残忍bdsm变态

Global EditionASIA 中文雙語Fran?ais
Lifestyle
Home / Lifestyle / Health

New obesity treatment lowers body weight in animal study

Xinhua | Updated: 2017-10-19 11:30
Share
Share - WeChat

An experimental treatment involving injection of engineered proteins significantly lowered body weight, blood insulin, and cholesterol levels in obese mice, rats and monkeys, according to a study published Wednesday in the US journal Science Translational Medicine.

The results could pave the way for urgently needed alternatives to bariatric surgery for treating obesity in humans -- the rates of which have nearly tripled worldwide since 1975, said researchers from the pharmaceutical company Amgen.

Previously, observations in mice, rats and humans have found that the lean ones appear to have elevated blood concentrations of a protein called GDF15 compared to their obese counterparts, they explained.

Because GDF15 breaks down too quickly in the blood and is difficult to produce in substantial quantities, the scientists generated two different versions of GDF15 that were more stable in the circulation and led to higher yields.

Both versions effectively decreased body weights for obese mice and cynomolgus monkeys.

Interestingly, Xiong and colleagues further showed that the GDF15 regimen altered food preferences in mice, leading the animals to opt for lower calorie chow when offered a choice between standard food and an extra-rich condensed-milk diet.

In contrast, untreated mice gorged themselves on the high-calorie eats.

The researchers also determined that GDF15 activated a population of nerve cells called AP neurons that make up a portion of the gut-brain axis.

"In conclusion, we demonstrated a strong effect of GDF15 in lowering body weight in obese mice and monkeys," they wrote in their conclusion.

"Our data support potential use of GDF15 in the clinic, with properties that could benefit individuals with obesity and associated metabolic comorbidities."

Most Popular
Top
BACK TO THE TOP
English
Copyright 1995 - . All rights reserved. The content (including but not limited to text, photo, multimedia information, etc) published in this site belongs to China Daily Information Co (CDIC). Without written authorization from CDIC, such content shall not be republished or used in any form. Note: Browsers with 1024*768 or higher resolution are suggested for this site.
License for publishing multimedia online 0108263

Registration Number: 130349
FOLLOW US
 
主站蜘蛛池模板: 响水县| 旺苍县| 惠州市| 平塘县| 博湖县| 和田市| 巫山县| 江城| 胶州市| 肇州县| 斗六市| 郑州市| 苏尼特右旗| 屏山县| 康乐县| 奈曼旗| 浏阳市| 长沙市| 云浮市| 建瓯市| 南平市| 朔州市| 大连市| 高邑县| 延寿县| 岑溪市| 寻甸| 迭部县| 南川市| 甘孜| 新疆| 镶黄旗| 贵德县| 万源市| 林口县| 涪陵区| 社旗县| 五常市| 灵川县| 修水县| 赤城县|